Jaundice and Anoxic Renal Damage: Protective Effect of Mannitol.
نویسنده
چکیده
on non-jaundiced patients (Clairmont and Von Haberer, 1911; Aird, 1953 ; Zollinger and Williams, 1956). Considerable decreases in renal blood-flow have been shown to occur with traction on viscera during abdominal operations (de Wardener, 1955) or in shock (Lauson et al., 1944). It is possible that obstructive jaundice renders the kidney more sensitive to decreased blood-flow-that is, anoxia. Experiments were therefore carried out to test this hypothesis. Using unilaterally nephrectomized rats, the effect of clamping the remaining renal pedicle for 60 minutes was compared in jaundiced and non-jaundiced animals. Furthermore, observations were made on the effect of a mannitol diuresis on such
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عنوان ژورنال:
- British medical journal
دوره 1 5386 شماره
صفحات -
تاریخ انتشار 1964